Establishment of normal reference system in pediatric echocardiography based on BigData
10.3760/cma.j.issn.1004‐4477.2019.03.001
- VernacularTitle:基于大数据的儿科超声心动图标准参考体系建设
- Author:
Haomin LI
1
;
Jin YU
;
Yuhong WANG
;
Huilong DUAN
;
Jing Jing YE
;
Jianhua LI
;
Qiang SHU
Author Information
1. 浙江大学医学院附属儿童医院心脏中心
- Keywords:
Echocardiography;
Normal reference system;
Children;
BigData;
Z score
- From:
Chinese Journal of Ultrasonography
2019;28(3):185-191
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a pediatric echocardiographic normal reference system based on clinical BigData and overcome limitations such as insufficient sample size and diverse in methods of normalization . Methods Measurements were extracted from total 71 831 pediatric echocardiography reports in the past 5 years by using the Natural Language Processing ( NLP) technology . Among them ,a total of 12 732 reports were labeled as normal and were used to establish the normal reference system . A local regression ( LOESS ) approach was used to optimize both the reference value and variance across 5 grow th variables ( aortic diameter ,left atrium diameter ,left ventricle end‐diastolic endocardial diameter ,left main coronary artery diameter ,and right main coronary artery diameter) . T wo Z scores adjusted for age/sex and body surface area ( BSA ) were established respectively . In addition , 4 459 echocardiography reports with BSA information were used to evaluate these two Z scores . Results T wo Z scores generated from 4 459 reports showed pretty good normal distribution . T here were close strong correlations among two Z scores with Z scores generated based on the Pediatric Heart Network ( PHN ) . T he average correlation coefficient between BSA‐adjust Z scores and PHN Z scores was 0 .954 . T he average correlation coefficient between age/sex‐adjust Z scores and PHN Z scores was 0 .895 . T he results of this project were available as Z score calculator using the following link :http ://hdb .nbscn .org/zscore . Conclusions BigData provides a more efficient and better approach to establish normal reference systems in pediatric echocardiography .
