Value of conventional ultrasound combined with contrast-enhanced ultrasound in differential diagnosis of thyroid TI-RADS 3-5 nodules
10.3760/cma.j.issn.1004-4477.2019.02.007
- VernacularTitle:二维灰阶超声联合超声造影对甲状腺TI-RADS 3-5类结节鉴别诊断的价值
- Author:
Lina PANG
1
;
Weidong QIN
;
Jingrui HAN
;
Xiao YANG
;
Fen GU
;
Haijing LIU
;
Xiaodong ZHOU
;
Dingzhang CHEN
;
Wen LUO
Author Information
1. 空军军医大学第一附属医院超声科
- Keywords:
Contrast-enhanced ultrasound;
Thyroid nodule;
Thyroid imaging reporting and data system
- From:
Chinese Journal of Ultrasonography
2019;28(2):123-126
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic value of gray-scale ultrasound combined with contrast-enhanced ultrasound (CEUS) in thyroid imaging and reporting system ( TI-RADS) 3-5 nodules of American College of Radiology ( ACR) . Methods The 208 patients( 216 nodules) who underwent thyroid contrast-enhanced ultrasound examination from April 2014 to December 2016 were retrospectively analyzed . The ACR TI-RADS classification and contrast-enhanced mode of thyroid ultrasound were evaluated . The benign and malignant thyroid lesions were constructed through the analysis of contrast-enhanced mode of thyroid benign and malignant lesions in the past literature and the preliminary study of our group . Prediction model of gray scale combined with contrast-enhanced ultrasound for lesions were established . Besides ,the sensitivity ,specificity and accuracy of gray scale ultrasound combined with contrast-enhanced ultrasound prediction model for differential diagnosis of benign and malignant thyroid lesions were calculated based on the results of puncture biopsy or surgical pathology as the gold standard . Results Compared with pathological results , the positive predictive value , negative predictive value , accuracy , sensitivity and specificity of gray scale combined with contrast-enhanced ultrasound in evaluating thyroid nodules were 90 .8％ ,93 .3％ ,91 .2％ ,98 .8％ and 62 .2％ ,respectively . Conclusions Gray-scale ultrasound combined with contrast-enhanced ultrasound can provide clinical value in differential diagnosis of benign and malignant TI-RADS 3-5 thyroid nodules .
