The value of three-dimensional contrast-enhanced ultrasound fusion imaging in evaluating the ablation margin of radiofrequency ablation for hepatocellular carcinoma
10.3760/cma.j.issn.1004-4477.2019.02.003
- VernacularTitle:三维超声造影融合成像评估肝癌射频消融安全边界的价值
- Author:
Xiaoyu ZHOU
1
;
Guangliang HUANG
;
Jieyi YE
;
Xiaoer ZHANG
;
Longfei CONG
;
Xiaohua XIE
;
Xiaoyan XIE
Author Information
1. 中山大学附属第一医院超声医学科中山大学超声诊断与介入超声研究所
- Keywords:
Contrast-enhanced ultrasound;
three-dimensional;
Carcinoma;
hepatocellular;
Fusion imaging;
Radiofrequency ablation
- From:
Chinese Journal of Ultrasonography
2019;28(2):103-107
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare three-dimensional contrast-enhanced ultrasound ( 3DCEUS) fusion imaging and computed tomography ( CT ) fusion imaging in evaluating ablation margin ( AM ) after radiofrequency ablation ( RFA) for hepatocellular carcinoma ( HCC) . Methods The 3DCEUS images of 60 patients before and after RFA were collected . The AM was evaluated by the self-developed 3DCEUS fusion imaging technique . The consistency of AM evaluation was compared between 3DCEUS and CT fusion imaging . The risk factors of local tumor progression ( LTP) including AM were analyzed . Results The registration success rate of 3DCEUS fusion imaging was 96 .7％ ( 58/60) . Thirty-one cases were in the AM<5 mm group ,and 27 cases were in the AM ≥5 mm group . The consistency of AM evaluation between 3DCEUS and CT fusion imaging was good ( Kappa coefficient = 0 .895 , P < 0 .001) . During a follow-up period ranging 4 .2 to 18 months ,LTP was identified in 5 tumors (8 .6％ ,5/58) .The incidence of LTP with the AM<5 mm was higher than that with the AM ≥5 mm ( P =0 .033) . Conclusions 3DCEUS fusion imaging is feasible for AM evaluation immediately after RFA with high consistency with CT fusion imaging . AM<5 mm evaluated on 3DCEUS fusion immediately after RFA is a risk factor for LTP .
