Eoxinophilic FAsciitis: Report of a case.
- Author:
Jung Bock LEE
;
Su Chan KIM
;
Young Keun KIM
- Publication Type:Original Article
- MeSH:
Abdominal Pain;
Adrenal Cortex Hormones;
Biopsy;
Dyspnea;
Eosinophilia;
Eosinophils;
Fascia;
Fasciitis*;
Foot;
Histiocytes;
Humans;
Hypergammaglobulinemia;
Inflammation;
Leg;
Lymphocytes;
Male;
Physical Examination;
Pulmonary Fibrosis;
Raynaud Disease;
Sclerosis;
Skin;
Young Adult
- From:Korean Journal of Dermatology
1980;18(4):361-365
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Eosinophilic fasciitis is a syndrome which is characterized by scleroderma-like skin involvement, eosinophilia and hypergammaglobulinemia without significant systemic changes. The primary pathological alterations are thickening and inflammation of the deep fascia. The majority of the cases that have been reportecd respond to systemic corticosteroids. We describe a 19-year-old male patient with eosinophilic fasciitis. On physical examination, he showed tender, edematous, indurated and tight skin in the back and both lower legs, and the laboratory findings showed eosinophilia and mild hypergammaglobulinemia. He also had Raynaud phenomenon, mild dyspnea, abdominal pain, pulmonary function abnormalities and roentgenographic evidence of pulmonary fibrosis. Result of a biopsy showed sclerosis of dermia and intense infiltrations of eosinophils, lymphocytes and histiocytes and fibroais of panniculus and fascia. Treatment with systemic corticosteroids showed complete resolution of the skin lesions, but after withdrawal new scleroderma-like skin lesions developed in the dorsum of feet.
