Epidemiological characteristics and etiology analysis of 11 510 hospitalized children with hand, foot, and mouth disease
10.3760/cma.j.issn.1000-6680.2019.03.006
- VernacularTitle:11510例手足口病住院患儿的流行特征及病原学分析
- Author:
Meifen WANG
1
;
Zengqing DU
;
Tiesong ZHANG
;
Yunjiao LUO
;
Lijiang DU
;
Quan GAN
;
Tiantian FU
;
Junchao PENG
;
Wei MA
;
Zhiying LU
Author Information
1. 昆明市儿童医院感染一科 650228
- Keywords:
Hand,foot and mouth disease;
Enterovirus;
Epidemic characteristics
- From:
Chinese Journal of Infectious Diseases
2019;37(3):160-162
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the prevalence trends and etiology of hand,foot,and mouth disease (HFMD) in hospitalized children.Methods The clinical data of 11 510 cases of children hospitalized with HFMD from 2008 to 2017 in Department of Infection Diseases of Kunming Children's Hospital were collected,and to retrospectively analyze the characteristics,time distribution and pathogen distribution of the cases.Results Of the 11 510 children with HFMD,6 100 were male and 5 410 were female.There were 9 814 cases under 3 years old,1 696 over 3 years old.HFMD occurred throughout the year.The peak months of the disease were April to July,with the time distribution of single peak.There were 4 690 severe cases and 3 452 critical cases,accounting for 70.34％.The main pathogens detected were enteroviruses A71 (EV-A71),coxsackievirus A16 (CV-A16) and other enteroviruses (EV),with 3 803 cases (36.02％),1 122 cases (10.63％) and 3 401 cases (32.21％) respectively.EV-A71 and CV-A16 infections dominated from 2008 to 2013,while EV-A71 and other EV infection dominated from 2014 to 2017.Conclusions EV-A71,CV-A16 and other EV are the main pathogens of HFMD in Kunming.Critical HFMD cases are mainly caused by EV-A71 infection.
