The research progress of mild cognitive impairment in Parkinson's disease

VernacularTitle:帕金森病轻度认知功能障碍的研究进展
Author: Shan ZHANG ¹ ; Tao CHEN ; Yidong DENG ; Yanhui LIU ; Si TENG ; Benchi CAI ; Jiali SU ; Jie LIN
Author Information

1. 海南省人民医院神经内科
Keywords: Parkinson disease; Cognition disorders; Review
From: Journal of Chinese Physician 2019;21(3):467-470
CountryChina
Language:Chinese
Abstract: Parkinson's disease (PD) is a neurodegenerative disease characterized by degeneration and deletion of dopaminergic neurons in the substantia nigra and a pathological feature of the Louis body.The clinical manifestations including non motor symptoms and motor symptoms.Cognitive impairment (CI)is one of the most common non motor symptoms in patients with PD,Which includes mild cognitive impairment (MCI) and dementia.MCI is an early manifestation of dementia in PD.Therefore,early diagnosis and treatment of MCI are very important for the prognosis of PD.The epidemiology,risk factors,heredity,biomarkers,imaging,diagnosis and treatment of MCI in PD are reviewed in this paper.