Research progress of ClC-3 in endometriosis
10.3760/cma.j.issn.1008-1372.2019.02.050
- VernacularTitle:ClC-3在子宫内膜异位症中的研究进展
- Author:
Yanan PI
1
;
Jing CAO
;
Shuang HOU
;
Suiyang ZHOU
;
Xiaohong QIU
Author Information
1. 哈尔滨医科大学附属第二医院妇产科 150001
- Keywords:
Endometriosis;
Chloride channels;
Cell movement;
Review
- From:
Journal of Chinese Physician
2019;21(2):319-320,封3
- CountryChina
- Language:Chinese
-
Abstract:
Chloride Channel-3 (ClC-3) is a member of the Cl2 channel superfamily,which is encoded by CLCN3 gene.It involves regulating electrical activity,cell volume,proliferation,migration,invasion,apoptosis and intracellular pH,which have become a hot spot of current research.In recent years,the research of ClC-3 in gynecological diseases is increasing day by day.This article will review the research progress of ClC-3 and benign and malignant gynecological diseases,especially the relationship between ClC-3 and the occurrence and development of endometriosis.
