Clinical Significance of Intraoperative Blood Flow into the Transplanted Liver in Early Allograft Dysfunction after Liver Transplantation
- VernacularTitle:肝移植术中入肝血流量对术后早期移植物功能不全的临床意义
- Author:
Rui GUO
1
;
Xiaohang LI
;
Feng LI
;
Qingpeng LIU
;
Xianliang LU
;
Bowen WANG
;
Yiman MENG
;
Lei YANG
;
Jialin ZHANG
Author Information
1. 中国医科大学附属第一医院肝胆外科暨器官移植科
- Keywords:
liver transplantation;
portal vein flow;
early allograft dysfunction;
risk factor
- From:
Journal of China Medical University
2019;48(3):240-244
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the risk factors associated with early allograft dysfunction (EAD) after liver transplantation. Methods We retrospectively analyzed the records of 138 patients who underwent liver transplantation from January 2006 to October 2016 in our department. Transplant recipients were divided into two groups:those who met the diagnostic criteria of EAD (EAD group) and those who did not (non-EAD group). We compared blood flow into the transplanted livers and other clinical features between the two groups using univariate and multivariate analysis. Results Intraoperative portal vein flow (PVF) maximum was significantly different between the two groups. Multivariate analysis revealed that intraoperative PVF maximum ＜1 600 mL/min was the only independent risk factor for the occurrence of EAD after liver transplantation in this cohort. Conclusion Intraoperative PVF maximum ＜1 600 mL/min is an independent risk factor for the occurrence of EAD after liver transplantation. Measuring intraoperative blood flow into the transplanted liver in liver transplant recipients may help identify patients at risk for developing EAD.
