Progress of obsessive-compulsive disorder in diffusion tensor imaging
10.3760/cma.j.issn.1674-6554.2019.04.017
- VernacularTitle:强迫症弥散张量成像研究进展
- Author:
Qiumeng GU
1
;
Zhen WANG
Author Information
1. 上海交通大学医学院附属精神卫生中心临床心理科 200030
- Keywords:
Obsessive-compulsive disorder;
Diffusion tensor imaging;
Diffusion tractography
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2019;28(4):375-379
- CountryChina
- Language:Chinese
-
Abstract:
Diffusion tensor imaging (DTI),a noninvasive MRI technique for measuring the integrity and direction of white matter in the brain,is a promising method to explore the pathogenesis of obsessive compulsive disorder (OCD).At present,the etiological research of OCD suggests that,in addition to the classical cortical-striatum-thalamus-cortical (CSTC) circuit,the parietal lobe,temporal lobe,occipital lobe and other regions of the brain are also involved in the pathogenesis of OCD.White matter fibers are important structure of material information communication in various brain regions and affected by individual neurodevelopment.Therefore,it is very important to explore the characteristics of white matter fiber in the brain of patients with OCD by using diffusion tensor imaging technology clarifying its role in the occurrence of OCD.This paper reviews the studies on uncinate fasciculus,superior longitudinal fasciculus,corpus callosum in adult DTI studies and the progress of DTI studies on children and adolescents.
