The risk factors and prevention for Alzheimer's disease
10.3760/cma.j.issn.1674-6554.2019.04.004
- VernacularTitle:阿尔茨海默病的风险因素及其预防
- Author:
Kaixin DOU
1
;
Lan TAN
;
Jintai YU
Author Information
1. 青岛大学附属青岛市市立医院神经内科 266071
- Keywords:
Alzheimer's disease;
Risk factors;
Risk models;
Prevention
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2019;28(4):305-310
- CountryChina
- Language:Chinese
-
Abstract:
With the aggravation of worldwide population aging,Alzheimer's disease (AD) has been an enormous impact on public health nowadays.Previous studies showed the incidence of AD has been declining in some high-income countries over three decades,which may be associated with improvement of living environment,education and medical care conditions.Therefore,evaluation risk factors of AD and take corresponding preventive measures has become an urgent problem to delay the occurrence and progress of AD.The mainly non-modifiable risk factors including age,gender,family history of genetic disease and genetic factors.Several modifiable risk factors are also confirmed to increase risk of AD occurrences,such as low education,hypertension and obesity in mid-life,diabetes mellitus,less physical activity,current smoking and depression.Various existing risk models for identifying individuals with high risk of AD have been developed in order to open new doors for targeted prevention.
