Role of microRNA in autoimmune and vasculitis
10.3969/j.issn.1000-484X.2019.02.025
- VernacularTitle:microRNA在自身免疫及血管炎性疾病发病中的作用
- Author:
Ye-Ping LUO
1
;
Zuo-Cheng YANG
Author Information
1. 中南大学湘雅三医院儿科
- Keywords:
Vasculities;
Autoimmune;
microRNA
- From:
Chinese Journal of Immunology
2019;35(2):250-256
- CountryChina
- Language:Chinese
-
Abstract:
miRNAs are a novel class of small, non-coding RNAs that regulate the expression of multiple protein-encoding genes at the post-transcriptional level by bind to the 3'-untranslated region ( UTR) of their target messenger RNAs. Although miRNAs constitute only 3% of the human genome, they regulate approximately 90% of genes. In this study, we are going to introduce the role of microRNAs in autoimmune and vasculitis disease.