Advances in research on related mechanisms of immune-targeted therapy on osteosarcoma
10.3969/j.issn.1000-484X.2019.02.022
- VernacularTitle:骨肉瘤免疫靶向治疗相关机制的研究进展
- Author:
Xin-Xin ZENG
1
;
Sheng-Tao WANG
;
Peng GUI
;
Hao WU
;
Zhao-Xu LI
Author Information
1. 桂林医学院附属医院骨二科
- Keywords:
Osteosarcoma;
Targeted therapy;
Immunotherapy;
Signaling pathway
- From:
Chinese Journal of Immunology
2019;35(2):236-239
- CountryChina
- Language:Chinese
-
Abstract:
Osteosarcoma, originated from mesenchymal tissue, is one of the highest incidence of primary malignant bone tumors which were characteristic double peak distribution both in adolescents and elderly. Immune-targeted therapy could block the tumor cell signaling pathway and promote cancer cell death by apoptosis. Immune-targeted therapy is an effective treatment of anti-osteosarcoma after surgery and chemotherapy in recent years. The paper reviews the advances in latest research on the related mechanisms of the immune-targeted therapy on osteosarcoma, and hope to provide a theoretical basis for clinical treatment.
