The clinical, angiographic and percutaneous coronary intervention characteristics in young patients with chronic total occlusion
10.3969/j.issn.1004-8812.2019.01.006
- VernacularTitle:青年冠状动脉慢性完全闭塞患者临床、血管造影和经皮冠状动脉介入治疗特点
- Author:
Jian ZHANG
1
;
Quan-Min JING
;
Xiao-Zeng WANG
;
Ying-Yan MA
;
Geng WANG
;
Hai-Wei LIU
;
Bin WANG
;
Kai XU
;
Dan LIU
;
Ya-Ling HAN
Author Information
1. 北部战区总医院 全军心血管病研究所心内科
- Keywords:
Coronary artery disease;
Chronic total occlusion;
Percutaneous coronary intervention
- From:
Chinese Journal of Interventional Cardiology
2019;27(1):23-27
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the characteristics in clinical, angiographic and percutaneous intervention (PCI) aspects of patients with chronic total occlusion (CTO) across different age groups, especially in young patients. Methods This study retrospectively analyzed 195 cases of CTO lesions admitted to the Department of Cardiology, General Hospital of Northern Theater Command from 2009 to 2014. These 1951 patients with CTO had undergone PCI and were divided into the young CTO group (≤44 years), the middle-aged CTO group (45-59 years) and the senior CTO group (≥60 years) according to their age. All patients had objective evidence of angina pectoris or myocardial ischemia before PCI. All the clinical features, coronary angiographic results, PCI related data and hospitalization outcome were all derived from our hospital PCI archives. Results There were significant differences in male ratio, body mass index, smoking and, drinking habit, creatinine clearance, triglyceride and LDL levels across the three groups (all P<0.05), and the highest values were found in the young patient group. The prevalence of unstable angina pectoris, hypertension and stroke were lowest in the young patient group (all P<0.05). The number of stenotic vessels and CTO occlusion time were less in young patients (all P <0.05). There was no significant difference among the three groups in CTO vascular distribution, coronary collateral Rentrop degree, CTO lesion length, CTO lesion diameter and CTO lesion characteristics (blunt CTO, CTO with bridging collateral and proximal branch of CTO lesion). There were no significant differences among the three groups in the volume of contrast agent used, CTO operation time, average stent number and average stent length (P>0.05). The procedural success rate of target vessels, races complete revascularization and mean stent diameter were highest in the young patient group (P<0.001).Conclusions Young CTO patients had typical risk factors of coronary heart disease with higher PCI success rate to target vessels and complete revascularization rate, which may be related to the short history of CTO.
