Outcome analysis of 71 patients with laryngeal squamous cell carcinoma
10.3760/cma.j.issn.1008-6706.2019.08.001
- VernacularTitle:喉鳞状细胞癌71例诊疗分析
- Author:
Wendong WANG
1
;
Yong AO
;
Baojun ZHAO
;
Xing WANG
;
Jialei GU
;
Kejing WANG
;
Minghua GE
;
Liang GUO
;
Jinbiao SHANG
Author Information
1. 浙江省肿瘤医院头颈外科
- Keywords:
Laryngeal tumor;
Squamous cell carcinoma;
Diagnosis;
Treatment;
Surgery;
Lymph node metastasis;
Neck dissection;
Prognosis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;26(8):897-901
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prognosis relevant factors of laryngeal squamous cell carcinoma (LSCC).Methods From January 2013 to December 2013,the clinical data of 71 patients with LSCC who were initially treated in Zhejiang Cancer Hospital were retrospectively analyzed.Results Univariate analysis showed that there were statistically significant differences in survival rate between the group of supraglottic type and glottic type (60.0% vs.86.3% ,χ2 =6.284,P<0.05),the group of N0 and N+(41.7% vs.86.4% ,χ2 =16.803,P<0.01), the group of early and late stage(93.6% vs.50.0% ,χ2 =19.854,P<0.01).There were no statistically significant differences in survival rate between the group of age ≤50,>50-60,>60-70 and >70(88.9% vs.88.2% vs. 79.3% vs.62.5% ,χ2 =3.909,P>0.05),the group of T1+T2 and T3+T4(83.6% vs.62.5% ,χ2 =3.623,P>0.05),the group of high,medium,low differentiated and unsigned(75.0% vs.69.7% vs.83.3% vs.91.7% ,χ2 =3.780,P>0.05),the group of surgery,radiotherapy and surgery+radiotherapy (74.3% vs.90.9% vs.71.4% , χ2 =2.437,P>0.05).Multivariate analysis showed that age( P =0.003),treatment( P =0.048) had significant effect on the prognosis of patients,but tumor location(P=0.766),T stage(P=0.677),N stage(P=0.482),clinical stage(P=0.825),the degree of pathological differentiation(P=0.206) had no significant effect on the prognosis of patients.Conclusion More aggressive treatment should be supplied for patients with N+,advanced clinical stage and age whom the prognosis are usually poor. In addition, the proportion of tracheal tube extraction should be appreciated.
