Investigation of prevalence and risk predictors of depressive tendency in type 2 diabetic patients with peripheral neuropathy
10.3760/cma.j.issn.1008-6706.2019.04.007
- VernacularTitle:2型糖尿病合并周围神经病变患者抑郁倾向患病状况及危险因素调查
- Author:
Fuman DU
1
,
2
;
Hongyu KUANG
;
Binhong DUAN
;
Dana LIU
;
Xinyang YU
Author Information
1. 哈尔滨医科大学附属第一医院内分泌二病房 150001
2. 黑龙江省医院内分泌科
- Keywords:
Type 2 diabetes mellitus;
Peripheral neuropathy;
Depression;
Dody mass index;
Insulin resistance;
Depression self-rating scale;
Morbidity;
Risk factor
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;26(4):408-411
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence and risk predictors of depressive tendency in type 2 diabetic patients with peripheral neuropathy.Methods From May 2017 to December 2017,150 diabetic patients with peripheral neuropathy and 150 diabetic patients without peripheral neuropathy in the First Affiliated Hospital of Harbin Medical University were collected.The general clinical data,including age,sex,diabetic duration,height,weight,body mass index (BMI),fasting blood glucose (FBG),fasting insulin (FINS),homeostasis modal assessment-insulin resistance index(HOMA-IR),glycated hemoglobin(HbA1c),blood lipid and blood pressure were collected.The motor nerve and sensory nerve conduction velocity of lower limbs were measured by electromyograph.Zung depression self-rating scale(SDS) was used for self-rating of depression syndrome.Results There were 46 cases(30.67％) suffered from depression(SDS ＞50) in the neuropathic group,and 25 cases(16.67％) suffered from depression in the non-neuropathic group.The incidence rate of depression in the neuropathic group was significantly higher than that in the non-neuropathic group and tended to be severe (x2 =12.732,P =0.005).Non-conditional Logistic multivariate stepwise regression analysis showed that sex,the course of diabetes and low density lipoprotein (LDL) were associated with depressive tendency (x2 =3.994,P =0.049;x2 =5.334,P =0.032;x2 =6.172,P =0.020).Conclusion The prevalence of depression in diabetic patients with peripheral neuropathy is higher and tends to be severe.Sex,the course of diabetes and LDL are risk factors of depressive tendency.
