Systemic disseminated Mycobacterium fortuitum infection:one case report and literature review
10.12138/j.issn.1671-9638.20193781
- VernacularTitle:全身播散性偶发分枝杆菌病1例报告并文献复习
- Author:
Li-Sha LUO
1
;
Bai-Ling LUO
;
Wei TANG
;
Shuang-Linzi DENG
;
Xin-Yue HU
;
Rui-Chao NIU
;
Cheng-Ping HU
;
Jun-Tao FENG
Author Information
1. 中南大学湘雅医院呼吸内科 国家呼吸疾病临床学研究中心核心单位
- Keywords:
nontuberculosis Mycobacteria;
disseminated nontuberculous mycobacterial disease;
Mycobacterium fortuitum;
disseminated infection
- From:
Chinese Journal of Infection Control
2019;18(2):158-162
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical characteristics of systemic disseminated infection caused by Mycobacterium fortuitum (M.fortuitum), and improve the diagnostic rate and understanding of the disease.Methods One case of systemic disseminated M.fortuituminfection was reported, and analyzed in combination with relevant literatures.Results Patient was with multiple systemic involvement (including lung, lymph node, skin, joint), lymph node tissue culture was positive for M.fortuitum, patient was given clarithromycin+levofloxacin+linezolid for treatment, disease was remitted.Conclusion Systemic disseminated M.fortuituminfection is rare, and patient with GATA2 deletion and IFN-γautoantibody may be a potential mechanism, diagnosis is mainly based on pathological morphology and microbiological detection, but positive rate is low, diagnosis is difficult.