Ualcan-based analysis of caspase-7 expression and prognostic role in colon cancer
10.3760/cma.j.issn.1673-4904.2019.02.016
- VernacularTitle:基于Ualcan数据库分析caspase-7在结肠癌中的表达和意义
- Author:
Zhaopeng YAN
1
;
Rui WANG
;
Qi SU
Author Information
1. 中国医科大学附属盛京医院第八普通外科/结直肠肛门病外科
- Keywords:
Colonic Neoplasms;
Caspase-7;
Ualcan database
- From:
Chinese Journal of Postgraduates of Medicine
2019;42(2):158-160
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the expression of caspase-7 (CASP7) and its prognostic role in colon cancer. Methods CASP7 expression data was retrieved from Ualcan database, and the survival data of CASP7 down-regulated colon cancer patients was retrieved from Ualcan database and Oncolnc database. Results In colon cancer, the expression of CASP7 was down-regulated and indicated a relatively worse prognosis. The expression of CASP7 was correlated with KRAS and TP53I3. Conclusions CASP7 is down-regulated in colon cancer and indicates a worse prognosis.
