Osteochondral lesions of the talus:etiology, diagnosis, treatment and prospects
10.3969/j.issn.2095-4344.1183
- VernacularTitle:距骨软骨损伤:病因、诊断、治疗及前景
- Author:
Yu HAN
1
;
Fei CHANG
;
Zhende JIANG
;
Naibo FENG
Author Information
1. 吉林大学第二医院
- Keywords:
Talus;
Cartilage;
Bone Transplantation;
Tissue Engineering
- From:
Chinese Journal of Tissue Engineering Research
2019;23(15):2443-2449
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND: Osteochondral lesion of the talus is a common disease of foot and ankle surgery, which has the characteristics of high morbidity, high misdiagnosis rate and difficulty in curing. OBJECTIVE: To summarize the etiology, clinical manifestations, diagnostic methods, clinical grading, treatment methods, and new therapies such as cell therapy and tissue engineering for osteochondral lesion of the talus.METHODS: The first author retrieved PubMed databases for relevant articles. The keywords were "talus, cartilage". Initially, 535 articles were retrieved, and finally 70 articles were included in result analysis. RESULTS AND CONCLUSION: Trauma is still considered to be the main pathogenic factor of talus cartilage injury. According to the imaging findings, the clinical scope of talar cartilage injury can be accurately determined. The clinically applied therapies have certain shortcomings and limitations. Tissue engineering-based therapies are currently the most likely to cure osteochondral lesion of the talus.
