Antimicrobial modification for orthopedic metal implants:merits and demerits
10.3969/j.issn.2095-4344.1651
- VernacularTitle:骨科金属植入物抗菌修饰的优点与问题
- Author:
Jin LUO
1
;
Hai LAN
Author Information
1. 遵义医学院
- Keywords:
Prostheses and Implants;
Prosthesis-Related Infections;
Tissue Engineering
- From:
Chinese Journal of Tissue Engineering Research
2019;23(14):2254-2260
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND: Infection of orthopedic implants is a problem to be solved. Currently, scholars are trying to endow orthopedic implants with an anti-infection function, and the research on antibacterial activity of implants has been a hot topic. OBJECTIVE: To introduce the modification methods of orthopedic metal implants in recent years. METHODS: Science Direct online (2015-2019) , WanFang (2015-2018) and VIP (2015-2018) databases were retrieved for literatures using the keywords of "antimicrobial, coating" in English and Chinese, respectively. RESULTS AND CONCLUSION: The currently used antimicrobial modification for orthopedic implants mainly consists of the self-antibacterial modification of the implant and the antibacterial modification on the surface of the implant. The antibacterial modification methods on the surface of the implant mainly include electrochemical modification method, magnetron sputtering method, spraying method, chemical conversion method, laser surface modification method, plasma injection method, nanosphere photolithography, sol/gel method, hydrothermal method, layer-by-layer assembly and combined treatment of various methods. Each antimicrobial modification method has its own merits and demerits.
