Nanomaterials applied in tumor imaging diagnosis and treatment:an integration tendency
10.3969/j.issn.2095-4344.1666
- VernacularTitle:纳米材料应用在肿瘤诊断与治疗中:呈一体化的趋势
- Author:
Yue CHEN
1
;
Tianke ZHANG
;
Yong XU
Author Information
1. 天津医科大学第二医院泌尿外科
- Keywords:
Nanostructures;
Neoplasms;
Molecular Targeted Therapy;
Tissue Engineering
- From:
Chinese Journal of Tissue Engineering Research
2019;23(14):2241-2247
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND: With the rapid development of nano-technology, the research and application of nanomaterials in biomedicine are increasing due to various advantages. It becomes a promising research direction in new anti-tumor methods. OBJECTIVE: To summarize the application of nanomaterials in imaging diagnosis and treatment of tumors. METHODS: The authors retrieved articles about the application of nanomaterials in tumor imaging diagnosis and treatment in WanFang, VIP, Elsevier and PubMed databases. The keywords were "nanophase materials, imaging diagnosis of tumor, nanocarriers, treatment of tumors, biological toxicity" in Chinese and English, respectively. RESULTS AND CONCLUSION: Due to its unique physical and chemical properties and plasticity, nanomaterials can become targeted medical materials that can carry anti-tumor drugs or active factors through specific modifications. Moreover, nanomaterials can adapt to different demands through various modifications and structural changes. Therefore, they have an unlimited prospect in the medical field. Currently, nanomaterials are not independent in the aspects of tumor diagnosis and treatment, but show an integration trend; that is, they are first targeted to tumor tissues, release active drugs during imaging diagnosis, or kill tumors through photothermal transformation.