Clinical application of autogenous adipose-derived stromal vascular fraction-assisted fat transplantation in the improvement of facial skin quality
10.3969/j.issn.2095-4344.1631
- VernacularTitle:自体脂肪来源基质血管组分辅助脂肪移植改善面部皮肤质量
- Author:
Yating YIN
1
;
Aijun ZHANG
;
Hao WANG
;
Pingping WANG
;
Jianhua LI
;
Minmin WEN
;
Peisheng JIN
Author Information
1. 徐州医科大学研究生院
- Keywords:
Adipose Tissue;
Tissue Transplantation;
Skin;
Face;
Tissue Engineering
- From:
Chinese Journal of Tissue Engineering Research
2019;23(12):1428-1433
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND: Many studies have shown that cell-assisted lipotransfer promotes the survival of fat implants, but there are few studies exploring stromal vascular fraction (SVF) -assisted fat transplantation for improving facial skin quality. OBJECTIVE: To evaluate the clinical effect of autologous adipose-derived SVF-assisted autologous fat transplantation in the improvement of facial skin quality. METHODS: From September 2016 to June 2018, in the Plastic and Cosmetic Center, the Affiliated Hospital of Xuzhou Medical University, 20 patients were recruited and then randomly divided into experimental group and control group, namely SVF-assisted fat transplantation and simple fat transplantation, respectively. A VISIA skin detector was used to detect facial skin quality of patients preoperatively and 6 months postoperatively, including spots, wrinkles, texture, pores, ultraviolet spots, brown spots, couperose skin and porphyrin. RESULTS AND CONCLUSION: The effect of improvement in wrinkles and texture in the experimental group was better than that of the control group, and the difference was statistically significant (P < 0.05). In terms of spots, pores and couperose skin, the therapeutic effect in the experimental group was better than that in the control group, but the difference was not statistically significant (P> 0.05). There was no significant difference between the two groups in the improvement of ultraviolet spot and brown spots. The porphyrin was not affected by the subjects. To conclude, SVF can promote the effect of fat transplantation in the improvement of facial skin quality.
