Effect of moistening room mirror combined with pranoprofen eye drops on dry eye and its influence on serum MMP-2 and STRA6 levels
10.3969/j.issn.1006-5725.2019.03.026
- VernacularTitle:润房镜联合普拉洛芬滴眼液治疗干眼症的效果及对血清MMP-2、STRA6水平的影响
- Author:
Shiyan CAO
1
;
Yuan CHEN
;
Yan ZHAO
;
Aiwei CHEN
Author Information
1. 贵州省人民医院眼视光科
- Keywords:
moistening mirror;
pranoprofen eye drops;
dry eye;
MMP-2;
STRA6
- From:
The Journal of Practical Medicine
2019;35(3):449-451
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the effect of moistening room mirror combined with pranoprofen eye drops on dry eye and its effect on serum MMP-2 and STRA6 levels. Methods 100 cases with dry eye disease treated in our hospital from January 2016 to August 2017 were randomly divided into the observation group and the control group. The control and observation group were treated with pranoprofen eye drops and moisturizing room mirror combined with pranoprofen eye drops. The clinical efficacy of the patients was evaluated, and the symptoms and the survival quality, MMP-2 and STRA6 of the patients were analyzed. Results Significant clinical efficiency was significantly higher in the observation group than in the control group (P < 0.05). BUT, SIt, visual related quality of life scores in the observation group were significantly higher than the control group (P < 0.05). Symptom score, MMP-2 and STRA6 levels in the observation group were significantly lower than the control group (P < 0.05).Conclusions The combination of moisturizing chamber mirror and pralofen eye drops in the treatment of dry eye can effectively improve the clinical efficacy and reduce the levels of MMP-2 and STRA6.