Therapeutic effects of heated humidified high flow nasal cannula oxygen therapy in patients with post-stroke systemic inflammatory response syndrome
10.3969/j.issn.1006-5725.2019.03.005
- VernacularTitle:经鼻高流量湿化氧气治疗对脑卒中后全身炎症反应综合征的疗效
- Author:
Ping HE
1
;
Jianqiang NI
Author Information
1. 无锡市人民医院神经内科
- Keywords:
stroke;
heated humidified high flow nasal cannula oxygen therapy;
systemic inflammatory response syndrome;
C-reactive protein;
NIHSS;
APACHE-Ⅱ;
CPIS;
mRS
- From:
The Journal of Practical Medicine
2019;35(3):356-359
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of heated humidified high flow nasal cannula oxygen therapy (HFNC) on patients with post-stroke systemic inflammatory response syndrome (SIRS). Methods Totally 78 patients with post-stroke SIRS were selected in the department of neurology of Wuxi People's Hospital and were randomly divided into HFNC group (n=40) and conventional therapy group (n = 38). The neurological impairment score (NIHSS) , APACHE-Ⅱ, clinical pulmonary infection score (CPIS) , C-reactive protein (CRP) of the 2 groups were recorded before and after the treatment. At the same time, modified Rankin score (mRS) of the two groups were also recorded. Results There was no significant difference in terms of morality and the number of patients with mechanical ventilation in the 2 groups. The 7-day APACHE Ⅱ, 7-day CPIS, 7-day SIRS cure rate, 14-day NIHSS and mRS of 3 months in HFNC group were higher than those in the conventional therapy group (P < 0.05).There was no significant difference in 7-day CRP, 14-day CRP and 14-day CPIS between HFNC group and conventional oxygen therapy group (P> 0.05). Conclusions HFNC can improve lung infection of patients with SIRS thus improve the recovery rate of SIRS. At the same time, it can improve the recovery of the neurological deficit and prognosis in acute stroke.
