PreliminaryapplicationofMRGDKIinearlydiagnosisandprognosisofcervicalspinalcordinjury
10.3969/j.issn.1002-1671.2019.03.033
- VernacularTitle:MR扩散峰度成像技术在急性颈髓损伤的早期诊断及预后演变中的初步应用
- Author:
Dongkui YANG
1
;
Guoshi LÜ
;
Wei LIU
;
Chengmei ZHAO
;
Kening XU
Author Information
1. 河北北方学院研究生院
- Keywords:
diffusionkurtosisimaging;
spinalcordinjury;
cervix;
fractionalanisotropy;
meandiffusivity;
meankurtosis
- From:
Journal of Practical Radiology
2019;35(3):469-472
- CountryChina
- Language:Chinese
-
Abstract:
Objective ToexplorethevalueofMR DKIinevaluationofmicrostructuredamageincervicalspinalcordinjury(CSCI) Methods 32casesofCSCIpatientsconfirmedbyclinicalexaminationand20casesofhealthycontrolgroupwereinvestigatedbyconventional MRIandDKIexamination.AccordingtoT2WIsignal,theinjurygroupweredividedintoA,Bgroup,Agroupofhighsignalgroup(n＝14)andBgroupofnegativegroup (n＝18).A,BgroupsandcontrolgroupweremeasuredbyFA,meandiffusivity(MD)and mean kurtosis(MK)valuesatdifferenttimes (acute,4 weeksafterinjury,2to3 monthsafterinjury)andthedata wereanalyzedby SPSS17.0statisticalsoftware.TheROCcurvewasusedtoevaluatetheabilityofdifferentparametersindiagnosingCSCI.Results In A,BgroupsFAvaluesdecreasedearlyandincreasedgradually,butwerealwayslowerthanthecontrolgroup,andthedifferencewas statisticallysignificant(P＜0.001).InAgroup MDvalueincreasedearlyanddecreasedgradually,butwashigherthanthecontrol group (P＜0.001).InAgroup MKvaluedecreasedearlyandincreasedsignificantly(P＜0.001).InBgroup MDvalueincreasedand MKvaluedecreasedintheacutephase(P＜0.001),lateron MDand MKvaluesgraduallytendtothecontrolgroup,thedifference wasnotstatisticallysignificant(P＞0.05).Conclusion DKIcannoninvasivelyreflectthemicroGdamageofCSCI,whichcannotbedisplayed byconventionalMRIfortheearlydetectionofspinalcordabnormalities.TheFAvalueisofhighdiagnosticvalue.
