RelationshipbetweenhighbilirubinrelatedencephalopathyandT1WIsignalintensityratio ofglobuspallidustoputamenintermneonates
10.3969/j.issn.1002-1671.2019.03.024
- VernacularTitle:苍白球与壳核T1WI信号比值在足月儿急性高胆红素相关脑病的临床研究
- Author:
Jiayu YIN
1
;
Wei SHEN
;
Meihai XU
;
Pingming LU
;
Jieqin WEI
Author Information
1. 南宁市第一人民医院磁共振室
- Keywords:
bilirubin;
globuspallidus;
T1 weightedimaging;
magneticresonanceimaging;
termneonate
- From:
Journal of Practical Radiology
2019;35(3):433-436
- CountryChina
- Language:Chinese
-
Abstract:
Objective TodeterminethevalueofT1WIsignalratioofbilateralglobuspallidustoputamenindiagnosisofhighbilirubin relatedencephalopathyoftermneonates.Methods ThecranialMRIsignalcharacteristicsandclinicaldataof105newbornswereanalyzed retrospectively.Accordingtothetotalserumbilirubin (TSB)andclinicalsymptoms,86caseswithoutriskfactorsofterm neonates weredividedinto4groups(Ⅰ~Ⅳand3groups(A~C).TheT1WIsignalintensityofbilateralglobuspallidusandputamenwere m easured and the ratio of G/P w as calculated.T he data of each group w ere co m pared and analyzed by t test and ANOVA.R O C curve ofG/Pratiowasperformedtopredicttheprogressofdisease.Results TherewasstatisticallysignificantdifferencebetweengroupⅠandgroupⅡ,groupⅠandgroupⅢ,groupⅠandgroupⅣ,groupⅡandgroupⅢ,groupⅡandgroupⅣ(P＜0.05),whereasno differencewasfoundbetweengroupⅢandgroupⅣ (P＞0.05).Comparingthethreegroupsdividedbyclinicalsymptoms,statistically significantdifferenceswereobserved(P＜0.05).TheROCcurverevealedthatforserum TSB,thepredictiveriskofhyperbilirubinemia with1.51and1.62,thepredictiveperformanceforhighbilirubinrelatedencephalopathywith1.70and1.69.Conclusion TheT1WI signalintensityratioofG/Ppotentiallyassistsinthediagnosisofhighbilirubinrelatedencephalopathy.Combinedwithclinicalmanifestations, itcanbecomprehensivelyanalyzeddialectically,therebyincreasingtheobjectiveaccuracyofdiagnosis.
