AnalysisofgenderdifferencesincoronaryarterydiseaseinpatientswithHIVinfectionbasedonCCTA
10.3969/j.issn.1002-1671.2019.03.010
- VernacularTitle:基于冠状动脉CT血管成像分析艾滋病患者冠状动脉疾病的性别差异
- Author:
Xiaomei DONG
1
;
Yonggao ZHANG
;
Jianbo GAO
;
Qingxia ZHAO
Author Information
1. 郑州大学第一附属医院放射科
- Keywords:
humanimmunodeficiencyvirus;
cardiovasculardisease;
atherosclerosis;
plaque;
gender
- From:
Journal of Practical Radiology
2019;35(3):378-382
- CountryChina
- Language:Chinese
-
Abstract:
Objective Toanalyzethedifferencesofthecoronaryarterycalciumscore,andtheprevalence,severity,characteristics ofcoronaryarteryplaquesbetweenAIDSinfectedfemaleandmale.Methods 158AIDSpatients(72femalesand86 males)and102 HIVGuninfectedpatients(49femalesand53 males)withsuspectedcoronaryarterydiseaseinourhospitalwereenrolledbetween March2017andFebruary2018.Patientsunderwentcoronarycomputedtomographyangiography (CCTA)bythethirdgenerationdual sourceforceCT.Thedifferencesofcoronaryarteryplaquesbetweengenderswereassessed.Results In HIVGuninfectedpatients,the prevalenceoftotalplaque,mixedplaque,severestenosisandtwoGvesseldiseasewassignificantlyhigherinmalethanfemale(allP＜0.05) andtheprevalenceofnonGcalcifiedplaquewassignificantlylowerinmalethanfemale(allP＜0.05).InAIDSpatients,theprevalence oftotalplaque,calcifiedplaque,severestenosisandCACS＞100wassignificantlyhigherin malethanfemale(allP＜0.05)andthe prevalenceofnonGcalcifiedplaqueandmixedplaquesignificantlywaslowerinmalethanfemale(allP＜0.05).Theprevalenceofthree ormorevesselsdiseasein maleAIDSpatientswassignificantlyhigherthanfemaleAIDSpatients.Conclusion MaleAIDSpatients havehighercoronarycalcifiedscoreandheaviercoronaryatherosclerosisburdens.Inaddition,femaleAIDSpatientshavelesscoronary atherosclerosisburdens,butmixedplaqueseemtobemorefrequently.
