Spindle cell lipoma/pleomorphic lipoma of soft tissue: a clinicopathologic analysis of 8 cases
10.13315/j.cnki.cjcep.2019.03.010
- VernacularTitle:梭形细胞/多形性脂肪瘤8例临床病理观察
- Author:
Rui ZHAN
1
;
Guang-Ming ZHAO
;
Ling-Chuan GUO
;
Wen-Juan GAN
Author Information
1. 南通大学附属吴江医院病理科
- Keywords:
lipoma;
spindle cell;
pleomorphic;
immunohistochemistry;
differential diagnosis
- From:
Chinese Journal of Clinical and Experimental Pathology
2019;35(3):295-298
- CountryChina
- Language:Chinese
-
Abstract:
Purpose To investigate the clinicopathological features, the diagnosis and differential diagnosis of spindle cell lipoma/pleomorphic lipoma (SCL/PL). Methods Eight cases of SCL/PL were studied by HE staining and immunohistochemistry. The literature was reviewed. Results Microscopically, the neoplasm consisted of spindle cells, mature adipocytes and thick rope-like collagen bundles in variable proportions with mucinous degeneration. The floret-like multinucleated giant cells were easy to be seen in the pleomorphic lipoma. Immunohistochemical analysis revealed that the tumor cells were positive for CD34 and vimentin. The Ki-67 was approximately 2％. The patients were followed up for 3 ～ 74 months, and no recurrence or metastasis occurred. Conclusion The SCL/PL is a special subtype of benign lipoma, surgery is considered the first choice, and outcome is favorable. The diagnosis and differential diagnosis of SCL/PL are important.
