Early enteral nutrition support dose selection in critically ill patients: a Meta analysis
10.3760/cma.j.issn.1671-0282.2018.08.010
- VernacularTitle:危重患者早期肠内营养支持剂量选择的Meta分析
- Author:
Meiqi YAO
1
;
Xiuqin FENG
;
Zhiting GUO
;
Xiaoxia HUANG
;
Yue MAO
;
Jiaying TANG
;
Haiyan ZHOU
;
Xiang YU
;
Jingfen JIN
Author Information
1. 浙江大学医学院附属第二医院护理部
- Keywords:
Enteral nutrition;
Critical care;
Dose;
Meta analysis
- From:
Chinese Journal of Emergency Medicine
2018;27(8):866-871
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically evaluate the optimal dose of early enteral nutrition support in critically ill patients.Methods Systematic search database including PubMed,Web of science,Scopus,CINAHL,CBM,CNKI.RCTs about early enteral nutrition dose selections in critically ill patients were chosen according to include and exclude criteria by two researchers independently.Cochrane system evaluation manual bias risk assessment was used to evaluate quality of literature.RevMan5.3 Meta analysis software was used to analyze the data.Results A total of 1 571 literatures were retrieved and 8 RCT studies were included,2 713 subjects in total.Meta analysis results showed that there were statistically significant differences in mechanical ventilation time,incidence of diarrhea,and utilization rate of gastro dynamic drugs between trophic feeding and full feeding (P＜0.05).There were no statistically significant differences in mortality,length of stay,incidence of nosocomial infections,reflux,vomiting,constipation,etc.(P＞0.05).Conclusions Trophic feeding has familiar effects on mortality,length of hospital stay compared to full feeding,but it can help to shorten ICU mechanical ventilation time,improve the gastrointestinal tolerability.
