The incidence of venous thrombosis related to totally implantable access port in upper arm in cancer patients and its risk factors
10.3969/j.issn.1008-794X.2019.03.008
- VernacularTitle:肿瘤患者上臂植入输液港并发上肢静脉血栓发生率及危险因素
- Author:
Xiaoxia QIU
1
,
2
;
Guangxin JIN
;
Yan GUO
;
Xuebin ZHANG
;
Lijuan LIU
Author Information
1. 海军军医大学卫生勤务学系 200433 上海
2. 上海交通大学医学院附属仁济医院肿瘤科
- Keywords:
implantable access port;
upper arm;
tumor patient;
upper extremity venous thrombus
- From:
Journal of Interventional Radiology
2019;28(3):242-246
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the incidence of venous thrombosis related to totally implantable access port (TIAP) in upper arm in cancer patients, and to discuss its risk factors. Methods The clinical data of a total of 1 724 patients, who received upper arm TIAP for deliverance of chemotherapy at authors' hospital during the period from February 2014 to April 2018, were collected. The general data of patients, catheterization, disease progression and incidence of venous thrombosis in upper limbs were analyzed. The univariate analysis and multivariate logistic regression analysis were used to determine the risk factors related to symptomatic thrombus. Results A total of 17 patients developed symptomatic venous thrombosis of the upper extremities, the incidence rate was 0.99％ (17/1 724) . The mean time interval from the implantation of upper arm TIAP to the diagnosis of thrombosis was 55.6 d (2-334 d) . Univariate analysis indicated that infection (P<0.01) and spontaneous catheter dislodgment (P<0.01) were significantly related to the risk of upper extremity venous thrombus (UEVT) . Multivariate binary logistic regression analysis revealed that infection (RR =16.85, P <0.01) and catheter spontaneous dislodgment (RR =101.09, P <0.01) were two important independent predictors for UVTE related to upper arm TIAP. Conclusion Infection and spontaneous catheter dislodgment are independent risk factors for upper arm TIAP-related thrombosis.
