New progress in the anti-tumor mechanism of curcumin
10.3760/cma.j.issn.1673-4246.2019.04.026
- VernacularTitle:姜黄素抗肿瘤作用机制及临床研究进展
- Author:
Yaxin SUN
1
;
Jingcheng CUI
;
Kai LIU
;
Haiyan WEI
;
Xiaochun HAN
;
Cuijuan WANG
Author Information
1. 山东省职业卫生与职业病防治研究院实验室
- Keywords:
Curcumin;
Antineopiastic drugs (TCD);
Chemoprevention;
Research progress;
Review
- From:
International Journal of Traditional Chinese Medicine
2019;41(4):426-429
- CountryChina
- Language:Chinese
-
Abstract:
Curcumin is derived from traditional Chinese medicine turmeric and can be used for chemoprevention and treatment of various cancers. Recent studies have shown that curcumin can participate in the regulation of various molecular signal transduction pathways, regulate the levels of reactive oxygen species, and regulate the inflammatory microenvironment to inhibit the occurrence of tumors. In addition, curcumin can inhibite the proliferation of tumor cells and promote apoptosis of tumor cells. Here, the paper reviews the mechanism of action of curcumin in cancer prevention and treatment and the new progress in the clinical trials, aiming to provide a basis for research in related fields.
