Combined Chinese and western medicine for endometrial receptivity: A meta analysis of clinical trials
10.3760/cma.j.issn.1673-4246.2019.02.027
- VernacularTitle:中西药联合改善子宫内膜容受性临床试验的meta分析
- Author:
Mei JIANG
1
;
Liran MA
;
Jia KANG
Author Information
1. 北京市鼓楼中医医院妇科 100009
- Keywords:
Integrated Chinese traditional and western medicine therapy;
Endometrial receptivity;
Fertilization in vitro;
Embryo transfer;
Meta-analysis;
Systematic review
- From:
International Journal of Traditional Chinese Medicine
2019;41(2):210-213
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systemically evaluate the effects of combined Chinese and western medicine in improving endometrial receptivity. Methods A search for relevant articles ran on the CNKI, WanFang, VIP, PubMed, EMBASE and Cochrane library. The randomized controlled trails of combined Chinese and western medicine therapy versus western medicine alone for improving endometrial receptivity were retieved The Revman 5.3 software was used for Meta-analysis according to Cochrane system evaluation method. Results A total of 7 randomized controlled trails involving 499 patients were included. There was statistically significant difference in the growth of clinical pregnancy rate [RR=1.78, 95％ CI (1.41, 2.26)], the increase of patients with endometrial thickness [MD=1.42, 95％ CI(1.27, 1.58)], the raise of the proportion with type A endometrium [RR=1.25, 95％ CI (1.07, 1.45)], the reduction of the patients with endometrial PI [SMD=-1.41, 95％ CI (-2.18,-0.64)]. There was no statistically significant difference in the reduction of endometrial RI [SMD=-1.11, 95％ CI (-2.52,0.30)]. Conclusions The therapy integrated Chinese and western medicine for endometrial receptivity is better than simple western medicine. But there is less literature on the high quality, suggesting that the methodology of clinical research should be further improved in the future.
