Research progress of TRIM14 in malignant tumors
10.3760/cma.j.issn.1673-422X.2018.12.006
- VernacularTitle:TRIM14在恶性肿瘤中的研究进展
- Author:
Zhixian YANG
1
;
Fei HOU
;
Haoyu LI
;
Zhiyong DENG
Author Information
1. 650118,昆明医科大学第三附属医院核医学科
- Keywords:
Neoplasms;
Cell proliferation;
Neoplasms metastasis;
Tripartite motif-containing 14
- From:
Journal of International Oncology
2018;45(12):731-734
- CountryChina
- Language:Chinese
-
Abstract:
Tripartite motif-containing 14 (TRIM14) is a member of tripartite motif family.Regulating innate immune response and affecting cell differentiation are the main physiological functions of TRIM14.It is reported TRIM14 expresses in various tumors such as non-small cell lung cancer,breast cancer,hepatocellular carcinoma,osteosarcoma and oral squamous cell carcinoma.The proliferation,invasion,metastasis,drug resistance of malignant tumors and the prognosis of patients with cancer can be affected via different mechanisms of TRIM14.
