Role of lncRNAs in accurate rejection after kidney transplantation
10.3760/cma.j.issn.1673-4203.2019.04.014
- VernacularTitle:长链非编码RNAs在肾移植术后急性排斥反应中的研究进展
- Author:
Yingxin FU
1
Author Information
1. 天津市第一中心医院肾移植科 300192
- Keywords:
Kidney transplantation;
Graft rejection;
Review;
long-chain non-coding RNA
- From:
International Journal of Surgery
2019;46(4):281-284
- CountryChina
- Language:Chinese
-
Abstract:
Kidney transplantation is the best treatment for end-stage renal disease.The types of the rejection can be divided into hyperacute rejection,accelerated rejection,acute rejection (AR) and chronic rejection according to the time of rejection after renal transplantation.Long noncoding RNAs (lncRNAs) play an important role in a variety of pathophysiological processes in the body,which can affect the stability of tissues.It is also closely related to various pathological processes such as acute kidney injury,glomerular disease and acute allograft rejection.What's more,the scholars found its huge potential for early diagnosis of AR after renal transplantation.This article will summarize the function of lncRNA in acute rejection of renal transplantation.
