Correlation analysis between thrombelastography and conventional coagulation indexes in breast cancer patients
10.3969/j.issn.1673-4130.2019.02.024
- VernacularTitle:乳腺癌患者血栓弹力图与常规凝血指标的相关性分析
- Author:
Zilan LYU
1
;
Binlin WANG
;
Bianqin GUO
;
Yang ZHANG
;
Lixiang WU
Author Information
1. 重庆大学附属肿瘤医院/重庆市肿瘤研究所/重庆市肿瘤医院检验科
- Keywords:
breast cancer;
thrombelastography;
coagulation;
platelets;
correlation analysis
- From:
International Journal of Laboratory Medicine
2019;40(2):218-221
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the correlation between thrombelastography (TEG) and conventional coagulation indexes in breast cancer patients, and to compare the differences between the two methods in the detection of coagulation function in breast cancer patients.Methods Retrospectively analyzed the clinical data of180patients with breast cancer who were performed TEG, coagulation and blood test in the same day in our hospital from November 2016to May 2017.Linear correlation and regression analysis were performed among the parameters.The differences of positive rates of TEG parameters and conventional coagulation indexes were compared.Results The R value of TEG parameters of breast cancer patients was positively correlated with K and APTT, and negatively correlated withα-Angle, MA, CI, DD, FDPs.K was positively correlated with APTT and TT, and negatively correlated withα-Angle, MA, FIB, DD, FDPs and PLT.α-Angle was positively correlated with MA, CI, FIB, DD, FDPs and PLT.MA was positively correlated with CI, FIB, DD, FDPs and PLT.CI was positively correlated with FIB, DD, FDPs and PLT.α-Angle, MA and CI were all negatively correlated with APTT and TT, the difference were statistically significant (P＜0.05).A linear regression equation of TEG parameters and coagulation indexes was obtained.There was no significant difference between TEG detection positive rate and conventional coagulation test (P＞0.05).Conclusion There are significant correlation between the TEG parameters and routine coagulation or platelet, and the results are consistent.
