Biomarkers for the diagnosis of Kawasaki disease
10.3760/cma.j.issn.1673-4408.2019.02.001
- VernacularTitle:川崎病诊断中的生物标志物
- Author:
Yanjie ZHU
1
Author Information
1. 复旦大学附属儿科医院心内科
- Keywords:
Kawasaki disease;
Biomarker;
Diagnosis
- From:
International Journal of Pediatrics
2019;46(2):77-80
- CountryChina
- Language:Chinese
-
Abstract:
Kawasaki disease (KD) is an acute,self-limiting systemic vascular syndrome that mainly occurs in infants and children under the age of five years,and is the leading cause of acquired heart disease in children.Kawasaki disease can lead to coronary dilatation,coronary aneurysm,which can cause myocardial infarction or death,seriously harm the health of infants and children,and thus early diagnosis is critically important.Till now the diagnosis is based mainly on the clinical symptoms for the lack of diagnostic laboratory tests.In recent years,many studies have been carried out to explore the potential biomarkers with high sensitivity and specificity in the early diagnosis of KD.The article reviews the progress of the related studies.