Pathogenic bacteria and drug sensitivity analysis of chronic suppurative otitis media and cholesteatoma in plateau area
10.16066/j.1672-7002.2019.01.006
- VernacularTitle:高原地区慢性化脓性中耳炎及中耳胆脂瘤的病原菌及药敏分析
- Author:
Yun LYU
1
;
Jian HE
;
Xudong WEI
;
Shaojie ZHANG
;
Yurong YAO
Author Information
1. 甘肃省人民医院耳鼻咽喉头颈外科
- Keywords:
Otitis Media,Suppurative;
Cholesteatoma,Middle Ear;
Colony Count,Microbial;
Microbial Sensitivity Tests
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2019;26(1):21-24
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To invest igate the distribution of pathogenic bacteria and the antibiotic susceptibility of otitis media in plateau areaandto guide clinical drug application rationally. METHODS Middle ear secretions were collected from 218 inpatients and outpatients(220 ears) with otitis media in our department from December 2016 to January 2018 and were performed by isolation and identification of pathogenic bacteriaand drug sensitivity test. RESULTS 1. 152 strains of microbes were isolatedincluding 125 casesof bacterial infection and 8 cases of fungal infection. 2. The gram-positive bacteria in middle ear effusions of chronic suppurative otitis media was higher than those of cholesteatoma, of which Staphylococcus aureuswas the most frequently isolated pathogen. While Pseudomonas aeruginosa was the highest in cholesteatoma. 3. The antibiotic sensitivity of pathogenic bacteria varies from strain to strain. CONCLUSION Staphylococcus aureusand Pseudomonas aeruginosa were the main pathogenic bacteria. Common pathogenic bacteria were resistance to penicillin and levofloxacin, which were commonly used in clinic. Therefore, bacterial culture should be carried out and rational drug use should be guided.
