Advances in diagnostic classification of erythroid proliferations in myeloid neoplasms
10.3760/cma.j.issn.1009-9921.2019.02.018
- VernacularTitle:红系增生髓系肿瘤的诊断分类演变
- Author:
Junjie SHENG
1
;
Suigui WAN
Author Information
1. 首都医科大学宣武医院血液科
- Keywords:
Erythroid proliferations in myeloid neoplasms;
French-American-British classification;
World Health Organization classification
- From:
Journal of Leukemia & Lymphoma
2019;28(2):125-128
- CountryChina
- Language:Chinese
-
Abstract:
Erythroid proliferations in myeloid neoplasms (MN-EP) is a group of heterogeneous diseases characterized by nucleated red blood cell proliferation and ineffective hematopoiesis in the bone marrow. Initial French-American-British (FAB) classification was used to diagnose and classify MN-EP according to morphological criteria. However, with the development of flow cytometry, cytogenetics and molecular biology techniques, FAB classification is obviously insufficient, which can not meet the clinical needs. Therefore, the World Health Organization (WHO) classification has introduced more accurate diagnostic classification standards and revised them several times. This paper reviews the research progress of MN-EP diagnostic classification.
