Findings and lessons from establishing Zika virus surveillance in southern Viet Nam, 2016
10.5365/wpsar.2018.9.2.014
- Author:
Lan Trong Phan
1
;
Quang Chan Luong
1
;
Thi Hong Hien Do
2
;
Cindy H Chiu
2
,
3
;
Thang Minh Cao
1
;
Thao Thi Thanh Nguyen
1
;
Hai Thanh Diep
1
;
Thao Phuong Huynh
1
;
Dung Tri Nguyen
4
;
Nga Hong Le
4
;
Satoko Otsu
2
;
Phu Dac Tran
5
;
Thuong Vu Nguyen
1
;
Masaya Kato
6
Author Information
1. Pasteur Institute, Ho Chi Minh City, Viet Nam
2. World Health Organization Viet Nam Country Office, Viet Nam
3. Tohoku University Graduate School of Medicine, Japan
4. Preventive Medicine Centre, Ho Chi Minh City, Viet Nam
5. General Department of Preventive Medicine, Ministry of Health, Viet Nam
6. World Health Organization Regional Office for the Western Pacific, Philippines
- Publication Type:Journal Article
- Keywords:
Zika virus;
outbreak;
surveillance;
Vietnam;
public health emergency of international concern;
re-emerging infectious diseases
- From:
Western Pacific Surveillance and Response
2019;10(2):22-30
- CountryWHO-WPRO
- Language:English
-
Abstract:
Objective:To document the evolution and optimization of the Zika virus (ZIKV) disease surveillance system in southern Viet Nam in 2016 and to describe the characteristics of the identified ZIKV-positive cases.
Methods:We established a sentinel surveillance system to monitor ZIKV transmission in eight sites in eight provinces and expanded the system to 71 sites in 20 provinces in southern Viet Nam in 2016. Blood and urine samples from patients who met the case definition at the sentinel sites were tested for ZIKV using real-time reverse transcription polymerase chain reaction at the Pasteur Institute in Ho Chi Minh City (PI-HCMC). We conducted descriptive analysis and mapped the ZIKV-positive cases.
Results:In 2016, 2190 specimens from 20 provinces in southern Viet Nam were tested for ZIKV at PI-HCMC; 626 (28.6%), 484 (22.1%), 35 (1.6%) and 1045 (47.7%) tests were conducted in the first, second, third and fourth quarters of the year, respectively. Of these tested specimens, 214 (9.8%) were ZIKV positive with 212 (99.1%) identified in the fourth quarter. In the fourth quarter, the highest positivity rate was those in age groups 30–39 years (30.0%) and 40–59 years (31.6%). Of the 214 ZIKV-positive patients, 210 (98.1%) presented with rash, 194 (90.7%) with fever, 149 (69.6%) with muscle pain, 123 (57.5%) with joint pain and 66 (30.8%) with conjunctivitis.
Discussion:The surveillance system for ZIKV disease underwent several phases of optimization in 2016, guided by the most up-to-date local data. Here we demonstrate an adaptable surveillance system that detected ZIKV-positive cases in southern Viet Nam.
- Full text:wpsar.2019.10.2-022.pdf
