Clinical effect comparison of three operations for one-stage radical correction of small left ventricle in children with tetralogy of Fallot
10.7507/1007-4848.201706021
- VernacularTitle:三种手术方式一期根治左心室较小型小儿法洛四联症的临床效果比较
- Author:
LI Junpeng
1
,
2
,
3
;
DONG Yanbo
4
;
ZHANG Huijun
4
;
SU Zhenyu
4
;
LI Hongying
4
;
ZHANG Man
4
;
LIU Yan
4
;
WANG Jun
4
;
HUANG Jiancheng
4
Author Information
1. 1. Department of Cardiac Surgery, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, P.R.China
2. 2. Zibo Integrated TCM &
3. Western Medicine Hospital, Zibo, 255026, Shandong, P.R.China
4. Department of Cardiac Surgery, The First Hospital of Hebei Medical University, Shijiazhuang, 050031, P.R.China
- Publication Type:Journal Article
- Keywords:
Tetralogy of Fallot;
small left ventricle;
enlargement of left ventricle;
one-stage radical operation
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2018;25(7):587-592
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical effect of three operations for one-stage radical correction of small left ventricle in children with tetralogy of Fallot (TOF). Methods We retrospectively analyzed the clinical data of 120 patients with left ventricular dysplasia and TOF undergoing one-stage radical surgery in the First Hospital of Hebei Medical University from December 2004 to May 2017. According to the different types of operation used, they were divided into 3 groups, including a routine group (30 patients, 16 males and 14 females, aged 11.58±2.05 months ranging from 3-24 months), a large patch group (40 patients, 22 males, 18 females, aged 11.22±2.24 months ranging from 3-25 months) who were treated with a large patch, and an enlarged ventricular septal defect group (50 patients, 26 males, 24 females, aged 10.17±2.15 months ranging from 3-22 months) using new left ventricular enlargement technique to enlarge ventricular septal defect. The clinical effect of the three operations were compared. Results The incidence of postoperative low cardiac output syndrome (6.0% vs. 40.0% vs. 50.0%, P<0.05), renal failure (4.0% vs. 37.5% vs. 46.7%, P<0.05), infection rate (10.0% vs. 50.0% vs. 66.7%, P<0.05), mortality (2.0% vs. 12.5% vs. 20.0%, P<0.05), ventilator-assisted time (8.34±5.24 h vs. 36.14±10.91 h vs. 38.58±10.12 h, P<0.05), ICU stay (4.13±1.01 d vs. 7.64±2.11 d vs. 8.03±3.03 d, P<0.05), hospital stay (10.48±4.26 d vs. 21.02±3.23 d vs. 22.52±2.93 d, P<0.05) and hospitalization costs (51 300±9 400 yuan vs. 103 200±39 300 yuan vs. 115 500±35 200 yuan, P<0.05) were less in the enlarged ventricular septal defect group compared with the other two groups. Conclusion The clinical effect of enlarged ventricular septal defect is better than that of the routine and large patch methods, and long-term efficacy should be further followed up.
