Passive pulmonary hypertension after cardiac surgery: from bench to bedside
10.7507/1007-4848.201809035
- VernacularTitle:围心脏手术期被动肺动脉高压：从基础到临床
- Author:
TAN Zhaoxia
1
;
LUO Nanfu
1
;
QIN Zhen
1
;
DU Lei
1
Author Information
1. Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, 610041, P.R.China
- Publication Type:Journal Article
- Keywords:
Pulmonary hypertension, passive;
left heart disease;
vasopressor agents;
additive effects
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2019;26(6):601-605
- CountryChina
- Language:Chinese
-
Abstract:
In left heart disease, pulmonary artery pressure would increase due to the elevated left atrial pressure. This type of pulmonary hypertension (PH) is belonged to type Ⅱ as a passive PH (pPH) in its classification. The essential cause of pPH is excessive blood volume. Recently, we have identified another type of pPH, which is induced by vasopressors. Vasopressor-induced pPH shares similar pathophysiological manifestations with left heart disease-induced pPH. pPH would, therefore, be aggressive if vasopressors were applied in patients with left heart disease, which may be common after cardiac surgery, because heart undergoing surgical trauma may require support of vasopressors. Unfortunately, pPH after cardiac surgery is often ignored because of the difficulty in diagnosis. To improve the understanding of pPH and its effect on outcomes, here we highlight the mechanisms of interaction between vasopressor-induced and left heart failure-induced pPH, and provide insights into its therapeutic options.
