Risk factors associated with surgical treatment of infective endocarditis
10.7507/1007-4848.201809042
- VernacularTitle:感染性心内膜炎手术危险因素分析
- Author:
CHEN Zonghui
1
,
2
;
LI Feng
1
,
2
;
ZHAO Jinlong
1
,
2
;
FU Liang
1
,
2
;
NI Yinkai
1
,
2
;
LU Zhexin
1
,
2
Author Information
1. Deparment of Cardiovascular Surgery of Shanghai Jiaotong University Affiliated Sixth People&rsquo
2. s Hospital, Shanghai, 200233, P.R. China
- Publication Type:Journal Article
- Keywords:
Infective endocarditis;
risk factors;
time of operation
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2019;26(6):558-564
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors of the death associated with infective endocarditis, and to evaluate the timing of surgical treatment of infective endocarditis. Methods We retrospectively analyzed the clinical data of 62 patients with infective endocarditis in our hospital between August 2015 and August 2017. There were 43 males and 19 females at age of 19–75 (46.1±16.6) years. The clinical data were divided into a death group and a survival group, a paravalvular leakage group and a no periannular leakage group, an emergency operation group and a non-emergency operation group.The risk factors of infective endocarditis and the choice of operation time were analyzed. Results Three of the 62 patients (4.8%) died after surgery. Postoperative perivalvular leakage (regurgitation over 2 mm) in 8 patients, accounting for 12.9% of the total. Univariate analysis showed that albumin content, creatinine level, total cardiopulmonary bypass time and ascending aorta occlusion time were significantly associated with early postoperative mortality (P<0.05). The results of logistic analysis showed that age, preoperative albumin level, creatinine level, total cardiopulmonary bypass time, and ascending aorta occlusion time were significantly associated with early postoperative perivascular leakage (P<0.05), and long ascending aorta occlusion time is an independent risk factor for early death (P<0.05). There was no statistical difference in early death and the perivalve leakage between the emergency operation and the non emergency operation. Conclusion Patients with infective endocarditis should accept early surgical treatment. The choice of surgical approach should be selected according to the actual situation of patients. And we should pay more attention to albumin and creatinine levels in preoperative patients. In the operation, to shorten extracorporeal circulation time and aortic clamping time can improve the prognosis of patients.
