A Case of Myocardial Injury after Phenylpropanolamine Ingestion.
10.4070/kcj.2000.30.3.365
- Author:
Wern Chan YOON
;
Dong Geun YEO
;
Hak Jun KIM
;
Jeong Ki PARK
;
Joon Hyung DOH
;
Jae Kean RYU
;
Ji Yong CHOI
;
Sung Gug CHANG
- Publication Type:Case Report
- Keywords:
Phenylpropanolamine;
Myocardial injury
- MeSH:
Appetite;
Arteries;
Chest Pain;
Coronary Angiography;
Coronary Vessels;
Creatine Kinase;
Dyspnea;
Eating*;
Electrocardiography;
Female;
Humans;
Middle Aged;
Myocardial Infarction;
Phenylpropanolamine*;
Tablets
- From:Korean Circulation Journal
2000;30(3):365-368
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Phenylpropanolamine is a sympathomimetic amine used widely as a decongestant or appetite suppressant. Reports of the myocardial injury from the use of phenylpropanolamine are rare and the mechanism of the myocardial injury is not known clearly. We experienced a case of myocardial injury after ingestion of phenyl-propanolamine. A 46-year-old woman was admitted because of chest pain and dyspnea after ingestion of 5 tablets of anorectic pill containing phenylpropanolamine 75 mg per tablet. The serum creatine kinase MB isoenzyme levels were elevated and electrocardiographic abnormalities suggesting myocardial infarction were seen in the precordial lead. In echocardiograpy, left ventricular anteroseptal wall motion was nearly akinetic but coronary angiography showed normal coronary arteries except sluggish blood flow in left anterior descending artery.
