Life-Threatening Thrombocytopenia Following Intravenous Contrast Media Infusion
10.3349/ymj.2018.59.1.158
- Author:
Mihwa PARK
1
;
Minjeong KIM
;
Jisun PARK
;
Jinhyun CHO
Author Information
1. Department of Internal Medicine, Inha University Hospital, Inha University School of Medicine, Incheon, Korea.
- Publication Type:Case Report
- Keywords:
Thrombocytopenia;
contrast media;
non-ionic;
hypersensitivity
- MeSH:
Acute Disease;
Administration, Intravenous;
Contrast Media/administration & dosage;
Contrast Media/adverse effects;
Humans;
Infusions, Intravenous;
Male;
Middle Aged;
Platelet Count;
Thrombocytopenia/etiology
- From:Yonsei Medical Journal
2018;59(1):158-161
- CountryRepublic of Korea
- Language:English
-
Abstract:
Radiocontrast media-induced acute severe thrombocytopenia is a very rare complication and potentially life-threatening. Here, we report the case of a 63-year-old male patient with severe acute thrombocytopenia following first exposure to intravenous non-ionic contrast media without immediate allergic reactions. His platelet count dropped from 107000/µL to 2000/µL after six hours of radiocontrast infusion. After administration of corticosteroid and transfusion of platelet concentrates, the platelet count returned gradually to normal within 5 days. To the best of our knowledge, non-ionic contrast media-induced isolated acute severe thrombocytopenia following no signs or symptoms of immediate allergic reaction has never been described.
