Predictors for Amputation in Patients with Diabetic Foot Wound
10.5758/vsi.2018.34.4.109
- Author:
Se Young KIM
1
;
Tae Hoon KIM
;
Jun Young CHOI
;
Yu Jin KWON
;
Dong Hui CHOI
;
Ki Chun KIM
;
Min Ji KIM
;
Ho Kyung HWANG
;
Kyung Bok LEE
Author Information
1. Department of Surgery, Seoul Medical Center, Seoul, Korea. kblee0925@icloud.com
- Publication Type:Original Article
- Keywords:
Diabetic foot wound;
Amputation;
Peripheral arterial occlusive disease;
Risk factors
- MeSH:
Amputation;
Arterial Occlusive Diseases;
Classification;
Dementia;
Diabetic Foot;
Heart Failure;
Humans;
Leukocytosis;
Lower Extremity;
Osteomyelitis;
Risk Factors;
Ulcer;
Wounds and Injuries
- From:Vascular Specialist International
2018;34(4):109-116
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Diabetic foot wound (DFW) is known as a major contributor of nontraumatic lower extremity amputation. We aimed to evaluate overall amputation rates and risk factors for amputation in patients with DFW. MATERIALS AND METHODS: From January 2014 to December 2017, 141 patients with DFW were enrolled. We determined rates and risk factors of major amputation in DFW and in DFW with peripheral arterial occlusive disease (PAOD). In addition, we investigated rates and predictors for amputation in diabetic foot ulcer (DFU). RESULTS: The overall rate of major amputation was 26.2% in patients with DFW. Among 141 DFWs, 76 patients (53.9%) had PAOD and 29 patients (38.2%) of 76 DFWs with PAOD underwent major amputation. Wound state according to Wagner classification, congestive heart failure, leukocytosis, dementia, and PAOD were the significant risk factors for major amputation. In DFW with PAOD, Wagner classification grades and leukocytosis were the predictors for major amputation. In addition, amputation was performed for 28 patients (38.4%) while major amputation was performed for 5 patients (6.8%) of 73 DFUs. Only the presence of osteomyelitis (OM) showed significant difference for amputation in DFU. CONCLUSION: This study represented that approximately a quarter of DFWs underwent major amputation. Moreover, over half of DFW patients had PAOD and about 38.2% of them underwent major amputation. Wound state and PAOD was major predictors for major amputation in DFW. Systemic factors, such as CHF, leukocytosis, and dementia were identified as risk factors for major amputation. In terms of DFU, 38.4% underwent amputation and the presence of OM was a determinant for amputation.
