Development of Prediction Equation of Diffusing Capacity of Lung for Koreans
- Author:
Yong Il HWANG
1
;
Yong Bum PARK
;
Hyoung Kyu YOON
;
Seong Yong LIM
;
Tae Hyung KIM
;
Joo Hun PARK
;
Won Yeon LEE
;
Seong Ju PARK
;
Sei Won LEE
;
Woo Jin KIM
;
Ki Uk KIM
;
Kyeong Cheol SHIN
;
Do Jin KIM
;
Hui Jung KIM
;
Tae Eun KIM
;
Kwang Ha YOO
;
Jae Jeong SHIM
Author Information
- Publication Type:Original Article
- Keywords: Korean; Pulmonary Diffusing Capacity; Diffusion; Carbon Monoxide
- MeSH: Carbon Monoxide; Diffusion; Female; Humans; Korea; Linear Models; Lung; Male; Methods; Nutrition Surveys; Pulmonary Diffusing Capacity; Smoke; Smoking; Thorax
- From:Tuberculosis and Respiratory Diseases 2018;81(1):42-48
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND: The diffusing capacity of the lung is influenced by multiple factors such as age, sex, height, weight, ethnicity and smoking status. Although a prediction equation for the diffusing capacity of Korea was proposed in the mid-1980s, this equation is not used currently. The aim of this study was to develop a new prediction equation for the diffusing capacity for Koreans. METHODS: Using the data of the Korean National Health and Nutrition Examination Survey, a total of 140 nonsmokers with normal chest X-rays were enrolled in this study. RESULTS: Using linear regression analysis, a new predicting equation for diffusing capacity was developed. For men, the following new equations were developed: carbon monoxide diffusing capacity (DLco)=−10.4433−0.1434×age (year)+0.2482×heights (cm); DLco/alveolar volume (VA)=6.01507−0.02374×age (year)−0.00233×heights (cm). For women the prediction equations were described as followed: DLco=−12.8895−0.0532×age (year)+0.2145×heights (cm) and DLco/VA=7.69516−0.02219×age (year)−0.01377×heights (cm). All equations were internally validated by k-fold cross validation method. CONCLUSION: In this study, we developed new prediction equations for the diffusing capacity of the lungs of Koreans. A further study is needed to validate the new predicting equation for diffusing capacity.
