Clinical Outcomes of Lung Transplantation: Experience at Asan Medical Center
10.5090/kjtcs.2018.51.1.22
- Author:
Yong Ho JEONG
1
;
Sehoon CHOI
;
Seung Il PARK
;
Dong Kwan KIM
;
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Korea. choishn@gmail.com
- Publication Type:Original Article
- Keywords:
Lung transplantation;
Extracorporeal membrane oxygenation (ECMO);
Survival
- MeSH:
Bone Marrow Transplantation;
Bronchiolitis Obliterans;
Chungcheongnam-do;
Critical Care;
Female;
Humans;
Idiopathic Interstitial Pneumonias;
Korea;
Lung Diseases;
Lung Diseases, Interstitial;
Lung Transplantation;
Lung;
Male;
Mortality;
Retrospective Studies;
Survival Rate;
Transplant Recipients;
Transplants;
Ventilators, Mechanical
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2018;51(1):22-28
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Lung transplantation is a life-saving procedure in patients with end-stage lung disease, and is increasingly performed in Korea. METHODS: We retrospectively evaluated the outcomes of patients who received a lung transplant at Asan Medical Center between January 2008 and December 2016. Thirteen of 54 patients experienced multiorgan transplantation; the remaining 41 who received only lung grafts were included. RESULTS: The mean age of the lung transplant recipients was 44.6 years; 27 were men and 14 were women. The most frequent reasons were idiopathic interstitial pneumonia (21 of 41 patients, 51.2%), interstitial lung disease (9 of 41, 22.0%), and bronchiolitis obliterans after bone marrow transplantation (7 of 41, 17.1%). The median waiting time was 47 days, and many patients received preoperative intensive care (27 of 41, 65.9%), ventilator support (26 of 41, 63.4%), or extracorporeal life support (19 of 41, 46.3%). All 41 patients received bilateral lung grafts. Ten deaths occurred (24.3%), including 5 cases of early mortality (12.2%) and 5 cases of late mortality (12.2%). The 1-, 3-, and 5-year survival rates were 78.9%, 74.2%, and 69.3%, respectively. CONCLUSION: Despite a high percentage of patients who required preoperative intensive care, the transplantation outcomes were acceptable.
