Epidemiology and Clinical Outcomes of Childhood Wilms Tumor in Korea.
- Author:
Won Suk SUH
1
;
Im Joo KANG
;
Hong Hoe KOO
;
Hoon KOOK
;
Soon Kee KIM
;
Hack Ki KIM
;
Hwang Min KIM
;
Heung Sik KIM
;
Kyung Duk PARK
;
Kyung Bae PARK
;
Sang Kyu PARK
;
Jae Sun PARK
;
Jun Eun PARK
;
Hyeon Jin PARK
;
Jong Jin SEO
;
Ki Woong SUNG
;
Hee Young SHIN
;
Hyo Seop AHN
;
Chang Hyun YANG
;
Keon Hee YOO
;
Kyung Ha RYU
;
Eun Sun YOO
;
Chuhl Joo LYU
;
Kwang Chul LEE
;
Kun Soo LEE
;
Soon Yong LEE
;
Young Ho LEE
;
Young Tak LIM
;
Pil Sang JANG
;
Nak Gyun CHUNG
;
Dae Chul JEONG
;
Hae Lim JUNG
;
Dong Whan CHO
;
Bin CHO
;
Yong Mook CHOI
;
Jeong Ok HAH
;
Pyoung Han HWANG
;
Tai Ju HWANG
Author Information
- Publication Type:Review
- Keywords: Wilms tumor; Epidemiology; Survival rate; Relapse rate
- MeSH: Child; Epidemiology*; Female; Humans; Incidence; Kaplan-Meier Estimate; Korea*; Male; Medical Records; Recurrence; Retrospective Studies; Survival Rate; Treatment Outcome; Wilms Tumor*
- From:Korean Journal of Pediatric Hematology-Oncology 2004;11(2):164-170
- CountryRepublic of Korea
- Language:Korean
- Abstract: PURPOSE: Wilms tumor is the most common malignant renal tumor in children. We investigated the epidemiology, clinical features and treatment outcome of the children with Wilms tumor in Korea during the recent 10 years. METHODS: Two hundred forty six patients were enrolled between January 1991 and December 2000 from 26 major hospitals in Korea. The data regarding the clinical features including sex, age, pathologic type, prognostic factor and treatment outcome of patients were analyzed retrospectively by review of patient's medical records. Kaplan-Meier survival curves were constructed, The differences between groups were analyzed by log-rank test. RESULTS: There were 130 males and 116 females. The incidence between the age of 1~4 years was the highest with 66.2%. The annual incidence rate per 1, 000, 000 population varied from 1.9 to 2.1. The 10 years overall survival rate according to sex, clinical stage, pathologic type and relapse were as follows: 88.6% in male, 90.9% in female, 100% in stage I, 94.7% in stage II, 92.1% in stage III, 63.4% in stage IV, 85.7% in stage V, 95.3% in favorable histology, 64.1% in unfavorable histology, 94.8% in non-relapse, and 40.9% in relapse. The relapse rate was 12%. The 10 years overall survival rate of 246 patients were 89.1%. CONCLUSION: Our results could provide the most recent and important clinical information on Wilms tumor of children in Korea.
