Endodontic biofilms: contemporary and future treatment options
- Author:
Yeon Jee YOO
1
;
Hiran PERINPANAYAGAM
;
Soram OH
;
A Reum KIM
;
Seung Hyun HAN
;
Kee Yeon KUM
Author Information
- Publication Type:Review
- Keywords: Antimicrobial resistance; Endodontic biofilm; Intracanal disinfection; Lactobacillus; Lipoteichoic acid
- MeSH: Bacteria; Biofilms; Disinfection; Homicide; Lactobacillus; Microbiota; Periapical Periodontitis; Virulence
- From:Restorative Dentistry & Endodontics 2019;44(1):e7-
- CountryRepublic of Korea
- Language:English
- Abstract: Apical periodontitis is a biofilm-mediated infection. The biofilm protects bacteria from host defenses and increase their resistance to intracanal disinfecting protocols. Understanding the virulence of these endodontic microbiota within biofilm is essential for the development of novel therapeutic procedures for intracanal disinfection. Both the disruption of biofilms and the killing of their bacteria are necessary to effectively treat apical periodontitis. Accordingly, a review of endodontic biofilm types, antimicrobial resistance mechanisms, and current and future therapeutic procedures for endodontic biofilm is provided.
