Two Cases of Malignant Lymphomas in Children with Selective IgA and IgG Subclass Deficiency.
- Author:
Ho Song NAM
1
;
Hoon KOOK
;
Kyung Ran SON
;
Hee Jo BACK
;
Seok Joo KIM
;
Ji Shin LEE
;
Tai Ju HWANG
Author Information
1. Department of Pediatrics, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Gwangju, Korea. hoonkook@chonnam.ac.kr
- Publication Type:Case Report
- Keywords:
Hodgkin's lymphoma;
Non-Hodgkin's lymphoma;
IgA deficiency;
IgG subclass deficiency;
Immunodeficiency
- MeSH:
Child*;
Hodgkin Disease;
Humans;
IgA Deficiency;
Immunoglobulin A*;
Immunoglobulin G*;
Lymphoma*;
Lymphoma, B-Cell;
Lymphoma, Large B-Cell, Diffuse;
Lymphoma, Non-Hodgkin
- From:Korean Journal of Pediatric Hematology-Oncology
2004;11(2):253-259
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Selective IgA deficiency is one of the most common primary immunodeficiency. Some patients with IgA deficiency also have deficits in one or more immunoglobulin G subclasses. It has been estimated that up to 25% of patients with certain primary immunodeficiencies will develop tumors, primarily B-cell lymphomas during their lifetime. We hereby present 2 cases of malignant lymphomas, one diffuse large cell lymphoma and another mixed cellularity Hodgkin's disease, respectively, which developed in patients with selective IgA and IgG subclass deficiency.
