A Case of Mesenteric Castleman's Disease with Systemic Involvement.
- Author:
Myung Seok SHIN
1
;
Sun Young KIM
;
Ji Young SUL
;
Jin Man KIM
;
Nak Gyun CHUNG
;
Bin CHO
;
Dae Chul JEONG
;
Kyung Deok PARK
;
Hack Ki KIM
Author Information
1. Department of Pediatrics, The Chungnam National University College of Medicine, Daejeon, Korea. sunyoung@cnuh.co.kr
- Publication Type:Case Report
- Keywords:
Castleman's disease;
Mesentery;
Hyaline-vascular type
- MeSH:
Biomarkers;
Child;
Fever;
Giant Lymph Node Hyperplasia*;
Humans;
Lymph Nodes;
Lymphoproliferative Disorders;
Mesentery;
Plasma Cells;
Sweat
- From:Korean Journal of Pediatric Hematology-Oncology
2004;11(2):280-285
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Castleman's disease (CD) is a lymphoproliferative disorder of unknown origin and rarely occurs in children. It has been further classified into two major subgroups: solitary or localized and multicentric CD. Furthermore, there are two main histological variants: hyaline-vascular, plasma cell types. Clinically, hyaline-vascular type is rarely associated with systemic symptoms, but the plasma cell type is frequently associated with the constitutional symptoms of fever, malaise, night sweat and the abnormal laboratory markers. Surgical excision of the affected lymph node plays an important role in the treatment of this disease. We encountered a case of the hyaline-vascular type CD located in the mesentery with systemic involvement. The clinical and biochemical abnormal findings improved after surgical resection of the involved lymph node.
